karppaus.infon arkistoitu foorumi

In my opinion, there’s nothing worse than a medication that is supposed to help lower your cardiovascular risk, but then likely ends up removing all of the potential benefits by taking away your ability to be physically active! Likely the greatest risk factor for heart disease is physical inactivity, so don’t prescribe statins that make people sit on the couch. At least have them try another medication to see if it a lesser negative impact on being active.

Now for the conspiracy theory: what if the trials were rigged? What if the researchers just hid the evidence they didn’t like and doctored the results to make it look good for Keys? What if Keys himself did a study on his pet theory, found out that the theory was bunk…and then just hid the results and pretended it never happened? And what if nobody noticed, and everyone took those doctored studies as “proof” that saturated fat causes heart disease?

It sounds ridiculous, but actually, that’s exactly what happened.

The two newer studies, the ones that uncovered the previous data suppression, both pointed out that the extremely high levels of Omega-6 PUFA in these interventions were likely inflammatory and contributed to causing heart disease by increasing oxidative stress and inflammation. This is basically the Paleo perspective on those fats: you can learn more about PUFA in general here, and PUFA and heart health here. In other words, when you look at what the studies actually show, in light of more recent research on PUFA and heart health, you end up with something that looks a lot like Paleo!

Nutritional advice to reduce saturated fat and replace it with polyunsaturated fat was largely based on the results of the Sydney Diet-Heart Study and the Minnesota Coronary Experiment. Now that we know what these studies really found, will that advice change? Hopefully so!

Den medicinska ”vetenskapen” har varit fylld av svammel sedan urminnes tider när de i Platon anda auktoritärt hävdat den ena dogmatiska dårskapen efter den andra. Behöver man påminna om åderlåtningen som vara praxis in på 1800-talet eller dagens motsvarighet när man idag kemiskt åderlåter våra kroppar på ett av våra viktigaste ämnen, kolesterolet, med hjälp av statiner. Den minsta eftertanke gör att man inser att det kryllar av idioti inom dagens medicin.

Att man inom medicinen idag anser att kosten i stort sett saknar betydelse för vår hälsa är betecknande för sakernas tillstånd och när man ändå kommer med sina dogmatiska kostråd innebär de en katastrof för vår hälsa. Stupiditetens höjdpunkt inom medicinen är förstås att man ska undvika de mättade fetterna och istället äta fleromättade växtfetter som bevisligen gör våra kroppar sjuka och får oss att dö i förtid genom att sänka kolesterolhalterna i blodet.

Medicine and science are run by human beings, so there will always be crooks.

Saturated fats are NOT harmless. Shout it from the roof tops. THEY ARE PROTECTIVE.

One can forgive Peter's sarcastic note in this old post from 2009. The whole cholesterol affair is risible and worthy of the deepest contempt. The Emperor needs to be dragged through the mud backwards, after all the damage his minions have caused !

SepelvaltimoTaudin Riskitekijöiden InterventioProjektin*) (STRIP) 26-vuotisseurantatutkimus alkoi viime huhtikuussa.

HALOO TURKU, ODOTAMME TULOKSIA!

*) SuomenKielen AlkeisKurssille nuo pitäisi lähettää.

Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
A Comprehensive Review

The STRIP trial randomly assigned 1062 Finnish infants to dietary intervention versus control, with follow-up for up to 20 years. For the first 3 years, the intervention focused on lowering total fat and saturated fat, while also increasing unsaturated fats from canola oil, other vegetable oils, and fish. At 3 years, no differences were seen in body weight, even among children most compliant with the low-fat diet.234 Subsequently, the intervention group received comprehensive dietary counseling, including to replace saturated fat with unsaturated fat, reduce salt intake, replace refined grains/cereals with whole grains, increase dietary fiber, increase fruits and vegetables, avoid smoking, and be physically active.235 The control group received only basic health education. Unsurprisingly, this comprehensive lifestyle advice, in comparison with no intervention, improved metabolic health.235 These results provide little inference on the specific effects of lowering saturated fat or dairy fat among children.

In sum, butter appears relatively neutral for cardiometabolic health, consistent with findings for total saturated fat

https://twitter.com/Dmozaffarian/status ... 0417018880

STRIP:issä poltettiin PALJON rahaa. Mitä saatiin? EI MITÄÄN!

Kolesterolitutkijat ovat ihmeissään ja pettyneitä. 12 000 suuren riskin potilaan 4 vuotiseksi tarkoitettu ACCELERATE-tutkimus keskeytettiin, kun kuolleisuus ei vähentynytkään, vaikka LDL aleni 35 % ja HDL-suureni yli 100 %.
Kolesterolin alentaminen ei ehkäise sydäntauteja

1. Ancel Keys, Seitsemän maan tutkimus 1958 - 1964

2. Pohjois-Karjala projektin esihanke 1960-luvun alussa Ilomantsissa menetelmäkehittelynä kliinisine havaintoineen. Suomalaiset tutkijat olivat Ancel Keysin kouluttamia A.C.:lle pystytetyssä Minnesotan tutkimuslaitoksessa.

3. Suomalainen mielisairaalatutkimus 1959 - 1971

4. Sydney Diet Heart Study 1966 -1973

5. The Minnesota Coronary Experiment (MCE), a randomized controlled trial conducted in 1968-73. Tämä tutkimus tehtiin Minnesotassa (USA), A.C.: kotikentällä

6. Varsinainen Pohjois-Karjala Projekti 1972 - 1997

...This paragraph stuck out as a nice warning, still applicable to the lipid hypothesis today, which we see crumbling before out eyes. How many have died prematurely of medical dogma?

“I am not against the industry, quite the opposite, entrepreneurship is crucial for translation, development, and growth. However, corporations should not be asked to practically perform the assessments of their own products [20]. If they are forced to do this, I cannot blame them, if they buy the best advertisement (i.e., “evidence”) for whatever they sell.

To this, I will just add that ‘oxidised’ LDL is particularly pro-coagulant. It reduces Nitric Oxide synthesis in the endothelium, triggers platelet activation and damages the endothelium. Thus the condition known as ‘dyslipidaemia’ is particularly dangerous. Dyslipidaemia consists of low HDL, high VLDL and more ‘oxidised’ LDL. It is usually caused by insulin resistance a.k.a. the metabolic syndrome a.k.a. pre-diabetes.

So, ahem yes, blood borne lipoproteins do have a role to play in CVD. The role is not key, but it is there. I thought I should get that off my chest.