Eläinperäisen proteiinin saanti korreloi käänteisesti kokonaiskuolleisuuden ja sydänkuolleisuuden kanssa. Kasviperäisillä proteiinilla ei tällaista korrelaatiota ollut. Eli runsas eläinproteiinin saanti pidensi ikää, kasviproteiini ei.
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Animal protein intake is inversely associated with mortality in older adults: the InCHIANTI study
Tomás Meroño, PhD, Raúl Zamora-Ros, PhD, Nicole Hidalgo-Liberona, MSc, Montserrat Rabassa, PhD, Stefania Bandinelli, MD, Luigi Ferrucci, MD, PhD, Massimiliano Fedecostante, MD, Antonio Cherubini, MD, PhD, Cristina Andres-Lacueva, PhD
The Journals of Gerontology: Series A, glab334,
https://doi.org/10.1093/gerona/glab334Published: 27 November 2021 Article history
Abstract
In general, plant protein intake was inversely associated with mortality in studies in middle-aged adults. Our aim was to evaluate the long-term associations of animal and plant protein intake with mortality in older adults.
Methods
A prospective cohort study including 1,139 community-dwelling older adults (mean age 75 years, 56% women) living in Tuscany, Italy, followed for 20 years (InCHIANTI study) was analyzed. Dietary intake by food frequency questionnaires and clinical information were assessed five times during the follow-up. Protein intakes were expressed as percentages of total energy. Time-dependent Cox regression models adjusted for confounders were used to assess the association between plant and animal protein intake, and mortality.
Results
During the 20-years of follow up (mean: 12y), 811 deaths occurred (292 of cardiovascular- and 151 of cancer-related causes). Animal protein intake was inversely associated with all-cause (HR per 1% of total energy from protein increase, 95%CI: 0.96, 0.93-0.99) and cardiovascular mortality (HR per 1% of total energy from protein increase, 95%CI: 0.93, 0.87-0.98). Plant protein intake showed no association with any of the mortality outcomes, but an interaction with baseline hypertension was found for all-cause and cardiovascular mortality (p<0.05).
Conclusions
Animal protein was inversely associated with all-cause and cardiovascular mortality in older adults. Further studies are needed to provide recommendations on dietary protein intake for older adults.