karppaus.infon arkistoitu foorumi

Of the 353 kids that had COVID infection information, the incidence rate was 8.6 per 100 person-years (95% CI 6.2-11.7) for participants testing negative for COVID-19. This wasn't significantly different compared with the prepandemic period (P=0.16).

But after COVID-19 infection, the incidence rate jumped to 14.0 per 100 person-years (95% CI 9.9-19.2). This was significantly higher than when they tested negative and also compared with the prepandemic period (P=0.04 vs pandemic COVID-19 negative; P<0.001 vs prepandemic period).

"We know that the virus can infect the pancreatic islets so it could be causing damage or change in the beta cells that make insulin," said Ziegler when discussing possible mechanisms behind this association. "Second, there is generalized inflammation during the infection and there may be a stimulation of the immune response. Third, there could be metabolic stress from the infection that affects the beta cells that make insulin.

Diet is another key factor. A diet high in refined carbohydrates and sugars can lead to spikes in blood sugar levels. Over time, this can cause the body to become less responsive to insulin.

Lean individuals who consume a lot of sugary foods and drinks or processed foods may be at higher risk for type 2 diabetes.

Unpopular food wards off diabetes and high blood pressure better than pills

A 64-year-old diabetic man from York has got his blood sugar levels back to normal by swimming 100 miles in 100 days.

Conclusions: This research demonstrates that most individuals mischaracterized their diet pattern
when compared to up to two 24-hour recalls. .

Furthermore, in recent years, ketone bodies, which have long been considered to be detrimental, have been reported to play a role as starvation signals, and thereby to have renoprotective effects, via the inhibition of mTORC1.

Syö vähemmän kuin kolme ateriaa päivässä voi suojata sinua tyypin 2 diabetekselta

Aikarajoitettu syöminen, paaston muoto, jossa syöt vähemmän mutta säännöllisiä aterioita tietyn aikaikkunan sisällä ja vältät syömistä 12–14 tunnin ajan (usein yön yli), voi vähentää tyypin 2 diabeteksen ja liikalihavuuden riskiä ja parantaa yleistä terveyttä. Uusi katsaus korostaa tämän syömismallin mahdollisia etuja.

Tutkijat löysivät yhteyden ihmisten nauttimien aterioiden määrän ja liikalihavuuden ja tyypin 2 diabeteksen esiintymisen välillä. Perinteiset neuvot kannustavat usein syömään kolme ateriaa päivässä välipalojen kera.

Tämä tutkimus kuitenkin viittaa siihen, että tällainen malli saattaa edistää liikalihavuutta. Jatkuva syöminen pitää insuliinitasot korkealla koko päivän, mikä voi johtaa insuliiniresistenssiin ja lopulta tyypin 2 diabetekseen, varsinkin Yhdysvalloissa yleisillä korkeakalorisilla ja sokeripitoisilla ruokavalioilla.

Aikarajoitettu syöminen mahdollistaa insuliini- ja glukoositasojen laskun, mikä parantaa insuliiniresistenssiä, aivojen terveyttä ja verensokerin hallintaa. Tämä syömismalli voi myös vähentää päivittäistä kalorien saantia noin 550 kalorilla ilman tiukkaa kalorilaskentaa.

Lisäksi se voi vaikuttaa positiivisesti suoliston mikrobiomiin auttaen estämään tulehduksia ja erilaisia ​​aineenvaihduntahäiriöitä. Se auttaa myös säätelemään ruokahalun hallinnasta ja energiatasosta vastaavia hormoneja.

Säännöllisten ateria-aikataulujen noudattaminen, mukaan lukien aamiaisen syöminen, ja samalla vähentää aterioiden ja välipalojen määrää, voi auttaa suojautumaan lihavuudelle ja tyypin 2 diabetekselle.

Kaikki aamiaiset eivät kuitenkaan ole tasa-arvoisia. Tutkimus ehdottaa terveellisten rasvojen ja proteiinien, kuten kananmunan, priorisointia sokeripitoisten aamiaismurojen ja leivonnaisten sijaan.

Vaikka aikarajoitetulla syömisellä on merkittäviä terveyshyötyjä, tutkijat havaitsivat, että muut paastomuodot, kuten usean päivän paasto, tarjoavat vain vähän etuja.

British Liver Trust Warns of Fatty Liver Disease Tsunami, Due to the Link Between Fatty Liver Disease and Type 2 Diabetes

The National Institute for Health and Care Excellence (NICE) estimates that by 2025, more than 5 million people in the UK will be diagnosed with diabetes. This means that the UK could be facing a tsunami of people newly diagnosed with fatty liver disease.

Two-thirds of people living with type 2 diabetes also have fatty liver disease[i] – but they may not be aware of it, warns the British Liver Trust. Fatty liver disease also significantly heightens the risk of developing type 2 diabetes. The charity urges people to get tested if they could be at risk, so both conditions can be managed effectively.

Summary
However, current evidence does not support the use of omega-3 supplementation in people with diabetes for the purpose of preventing or treating cardiovascular events. People with all types of diabetes are suggested to include fatty fish and foods high in omega-3 fatty acids in their diet twice a week, as is prescribed for the general population.

As I have written, a safe, effective and cheap solution to the type 2 diabetes epidemic already exists. To put it simply, type 2 diabetes, the condition of insulin resistance which afflicts 95% of people with diabetes, is reversible with a low-carb diet. The American Diabetes Association has even quietly acknowledged this. Numerous clinicians practice this and have published their results. Yet, as over 100,000 Americans still die from the condition annually, the American Diabetes Association and medical establishment steadfastly refuse to advocate for it.

Few people with diabetes understand their risk of liver disease

Ageing Research Reviews
Volume 99 August 2024
Review Article

True or false? Alzheimer’s disease is type 3 diabetes: Evidences from bench to bedside

https://doi.org/10.1016/j.arr.2024.102383

Abstract
Globally, Alzheimer's disease (AD) is the most widespread chronic neurodegenerative disorder, leading to cognitive impairment, such as aphasia and agnosia, as well as mental symptoms, like behavioral abnormalities, that place a heavy psychological and financial burden on the families of the afflicted. Unfortunately, no particular medications exist to treat AD, as the current treatments only impede its progression.The link between AD and type 2 diabetes (T2D) has been increasingly revealed by research; the danger of developing both AD and T2D rises exponentially with age, with T2D being especially prone to AD. This has propelled researchers to investigate the mechanism(s) underlying this connection. A critical review of the relationship between insulin resistance, Aβ, oxidative stress, mitochondrial hypothesis, abnormal phosphorylation of Tau protein, inflammatory response, high blood glucose levels, neurotransmitters and signaling pathways, vascular issues in AD and diabetes, and the similarities between the two diseases, is presented in this review. Grasping the essential mechanisms behind this detrimental interaction may offer chances to devise successful therapeutic strategies.